Caprie study moxifloxacin dose

Community-Acquired Pneumonia Recovery in the Elderly ...

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1/1/2006 · There was no difference in mortality between the 2 treatment groups (P =.5), and the majority of deaths occurred >7 days after receipt of the final dose of study drug. Only 6 moxifloxacin- and 3 levofloxacin-treated patients died during therapy or within the first 7 days after therapy.

Community-Acquired Pneumonia Recovery in the Elderly ...

Efficacy and safety of moxifloxacin in community acquired ...

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6/30/2014 · Conclusions. The efficacy and safety profiles of moxifloxacin at the recommended dose of 400 mg daily are characterized in this large observational study of hospitalized CAP patients from Eastern and Central Europe and the Middle East.

Efficacy and safety of moxifloxacin in community acquired ...

Moxifloxacin in the Treatment of Community-Acquired ...

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Moxifloxacin vs High-Dose Ceftriaxone ± Erythromycin (MOXIRAPID): Clinical Success Moxifloxacin monotherapy was clinically equivalent in efficacy to high-dose ceftriaxone with or without erythromycin at the TOC visit (5 to 20 days after end of study) in 317 patients hospitalized ) with CAP (primary endpoint) 85.7 86.5 0 10 20 30 40 50 60 70 80 ...

Moxifloxacin in the Treatment of Community-Acquired ...

Moxifloxacin Monotherapy Is Effective in Hospitalized ...

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5/15/2008 · Abstract. Background.The aim of this study was to show that sequential intravenous and oral moxifloxacin monotherapy (400 mg once per day) is as efficacious and safe as a combination regimen (intravenous ceftriaxone, 2 g once per day, plus sequential intravenous and oral levofloxacin, 500 mg twice per day) in patients hospitalized with community-acquired pneumonia.

Moxifloxacin Monotherapy Is Effective in Hospitalized ...

Community-Acquired Pneumonia Recovery in the Elderly ...

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Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE): Efficacy and Safety of Moxifloxacin Therapy versus That of Levofloxacin Therapy. ... after receipt of the final dose of study drug.

Community-Acquired Pneumonia Recovery in the Elderly ...

A brief review of moxifloxacin in the treatment of elderly ...

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A brief review of moxifloxacin in the treatment of elderly patients with community-acquired pneumonia (CAP) Anna M Ferrara ... and the only study entirely carried out on a population of ... et al. Community-acquired pneumonia recovery in the elderly (CAPRIE): efficacy and safety of moxifloxacin therapy versus that of levofloxacin. Clin ...

A brief review of moxifloxacin in the treatment of elderly ...

Community-Acquired Pneumonia Recovery in the Elderly ...

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receipt of the first dose of study drug), during treatment (be-tween days 3 and 5 after the start of treatment), and at the test-of-cure visit (between days 5 and 21 after the end of ther-apy). Sputum samples were collected before study drug was started. Cultures were performed if …

Community-Acquired Pneumonia Recovery in the Elderly ...

Efficacy and safety of moxifloxacin in community acquired ...

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The dose of moxifloxacin recommended for treatment The efficacy population included all patients who took of CAP in the study was 400 mg once every 24 hours, at least one dose of study medication and provided in- consistent with the local Summary of Product Charac- formation on the efficacy of treatment.

Efficacy and safety of moxifloxacin in community acquired ...

Efficacy and safety of moxifloxacin in community acquired ...

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Efficacy and safety of moxifloxacin in community acquired pneumonia: Prospective, multicenter, observational study (CAPRIVI).pdf R E S E A R C H A R T I C L E Open Access Efficacy and safety of ...

Efficacy and safety of moxifloxacin in community acquired ...

A Randomized Trial Comparing the Cardiac Rhythm Safety of ...

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CAPRIE Study Group† ... The dose of levofloxacin was adjusted for patients with creat- ... Patients randomized to moxifloxacin did not require dose adjustments in the presence of renal insufficiency. IV moxifloxacin and levofloxacin are formulated as uniquely colored infusions. It was therefore necessary to …

A Randomized Trial Comparing the Cardiac Rhythm Safety of ...

Moxifloxacin Hydrochloride Monograph for Professionals ...

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Antibacterial; 8-methoxy fluoroquinolone. 1 2 Uses for Moxifloxacin Hydrochloride. Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

Moxifloxacin Hydrochloride Monograph for Professionals ...

The Evaluation of a Standard Treatment Regimen of Anti ...

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4/6/2015 · The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB (STREAM) ... Selection of a moxifloxacin dose that suppresses drug resistance in Mycobacterium tuberculosis, by use of an in vitro pharmacodynamic infection model and mathematical modeling. ... Niederman MS, Choudhri S; CAPRIE Study Group. A ...

The Evaluation of a Standard Treatment Regimen of Anti ...

Efficacy and safety of moxifloxacin for community-acquired ...

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ORIGINAL ARTICLE Efficacy and safety of moxifloxacin for community-acquired bacterial pneumonia based on pharmacokinetic analysis Koichiro Yoshida • Niro Okimoto • Michihiro Kishimoto • Hiroshi Fukano • Hiroki Hara • Hirohide Yoneyama • Osamu Moriya • Masayoshi Kawanishi • Makoto Kimura • Toshiharu Matsushima • Yoshihito Niki Received ...

Efficacy and safety of moxifloxacin for community-acquired ...

Study: Moxifloxacin Highly Successful in Treating ...

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Study: Moxifloxacin Highly Successful in Treating Pneumonia in Elderly Patients October 27, 2004 -- A new study showed the antibiotic Avelox® (moxifloxacin HCl) was highly successful and safe in elderly patients with community-acquired pneumonia (CAP) compared to the antibiotic Levaquin® (levofloxacin). ... or CAPRIE, was presented today at ...

Study: Moxifloxacin Highly Successful in Treating ...

A Randomized Trial Comparing the Cardiac Rhythm Safety of ...

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The mortality rates during the observation period were 7.7% (n = 15) in the moxifloxacin group and 5.5% (n = 11) in the levofloxacin group. Thirteen of those deaths (50%) occurred > 7 days after the last dose of study drug was received: nine moxifloxacin-treated patients and four levofloxacin-treated patients.

A Randomized Trial Comparing the Cardiac Rhythm Safety of ...

Moxifloxacin Monotherapy Is Effective in Hospitalized ...

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All patients who were ran- in 17 countries between January 2004 and July 2005 and in domized, received at least 1 dose of study medication, and accordance with current guidelines of the International Con- underwent 1 observation after the start of the study were in- ference on Harmonization for Good Clinical Practice, the mod- cluded in the ...

Moxifloxacin Monotherapy Is Effective in Hospitalized ...

Management of Community-acquired Pneumonia: Fluoroquinolones

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In the Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE) study, intravenous/oral moxifloxacin therapy was associated with faster clinical recovery than intravenous/oral levofloxacin ...

Management of Community-acquired Pneumonia: Fluoroquinolones

The Evaluation of a Standard Treatment Regimen of Anti ...

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4/6/2015 · The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and …

The Evaluation of a Standard Treatment Regimen of Anti ...

Pharmacokinetics of consecutive oral moxifloxacin (400 mg ...

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The pharmacokinetic profile of moxifloxacin in Japanese patients with respiratory tract infection and an underlying disease should thus be considered safe and comparable with that in healthy adult men, and adjustment of dose may do not need for age, sex, body weight, or renal function.

Pharmacokinetics of consecutive oral moxifloxacin (400 mg ...

Clopidogrel Side Effects in Detail - Drugs.com

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11/19/2018 · In the CAPRIE study (n=19,185), gastrointestinal hemorrhage occurred in 2% of patients taking clopidogrel compared to 2.7% taking aspirin. Bleeding requiring hospitalization occurred in 0.7% clopidogrel-treated and 1.1% aspirin-treated patients. Common (1% to 10%): Abdominal pain, gastrointestinal hemorrhage, dyspepsia, diarrhea, nausea, gastritis

Clopidogrel Side Effects in Detail - Drugs.com

Pharmacokinetics of consecutive oral moxifloxacin (400 mg ...

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12/11/2015 · A population pharmacokinetic analysis was performed to investigate the pharmacokinetics of moxifloxacin (400 mg) following a once-daily oral administration in 28 patients with respiratory tract infection disease. The maximum plasma concentration and the area under the plasma concentration–time curve were 3.97 µg/ml and 51.74 µg·h/ml, respectively; these values were nearly equivalent to ...

Pharmacokinetics of consecutive oral moxifloxacin (400 mg ...
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