Glimepiride dose titration study

Glimepiride - FDA prescribing information, side effects ...

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3/16/2014 · The present study showed that glimepiride/metformin fixed-dose combination therapy was more effective in glycemic control than metformin uptitration, and was well tolerated in type 2 diabetic patients inadequately controlled by low-dose metformin monotherapy in Korea.

Glimepiride - FDA prescribing information, side effects ...

Efficacy of glimepiride/metformin fixed-dose combination ...

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11/27/2018 · Baseline creatinine clearance ranged from 10-60 mL/min. The pharmacokinetics of AMARYL were evaluated in the multiple-dose titration study and the results were consistent with those observed in patients enrolled in a single-dose study. In both studies, the relative total clearance of AMARYL increased when kidney function was impaired.

Efficacy of glimepiride/metformin fixed-dose combination ...

Amaryl Tablets (Glimepiride): Side Effects, Interactions ...

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Baseline creatinine clearance ranged from 10 to 60 mL/min. The pharmacokinetics of glimepiride were evaluated in the multiple-dose titration study and the results were consistent with those observed in patients enrolled in a single-dose study. In both studies, the relative total clearance of glimepiride increased when kidney function was impaired.

Amaryl Tablets (Glimepiride): Side Effects, Interactions ...

GLIMEPIRIDE - dailymed.nlm.nih.gov

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GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients. ... glimepiride 1 mg. Dur ing the titration period, the dose of.

GLIMEPIRIDE - dailymed.nlm.nih.gov

GUIDE study: double-blind comparison of once-daily ...

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Baseline creatinine clearance ranged from 10 to 60 mL/min. The pharmacokinetics of glimepiride were evaluated in the multiple-dose titration study and the results were consistent with those observed in patients enrolled in a single-dose study. In both studies, the relative total clearance of glimepiride increased when kidney function was impaired.

GUIDE study: double-blind comparison of once-daily ...

GLIMEPIRIDE - DailyMed

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The present study showed that glimepiride/metformin fixed‐dose combination therapy was more effective in glycemic control than metformin uptitration, and was well tolerated in type 2 diabetic patients inadequately controlled by low‐dose metformin monotherapy in Korea. This trial was registered with ClinicalTrial.gov (no. NCT00612144).

GLIMEPIRIDE - DailyMed

Efficacy of glimepiride/metformin fixed‐dose combination ...

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4/1/2007 · Study dose. The mean final dose for glimepiride was 3.8 mg/day (range 1–8) and for metformin 1,408 mg/day (500–2,000). Efficacy Changes in A1C. To evaluate the efficacy of glimepiride and metformin therapy in children and adolescents with type 2 diabetes, we evaluated the mean change in A1C from baseline to weeks 12 and 24 of treatment.

Efficacy of glimepiride/metformin fixed‐dose combination ...

Glimepiride Versus Metformin as Monotherapy in Pediatric ...

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Baseline creatinine clearance ranged from 10 to 60 mL/min. The pharmacokinetics of glimepiride were evaluated in the multiple-dose titration study and the results were consistent with those observed in patients enrolled in a single-dose study. In both studies, the relative total clearance of glimepiride increased when kidney function was impaired.

Glimepiride Versus Metformin as Monotherapy in Pediatric ...

NDC 16729-002 Glimepiride Glimepiride

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AMARYL® (glimepiride tablets) 1, 2, and 4 mg . DESCRIPTION . AMARYL ® (glimepiride tablets) is an oral blood-glucose-lowering drug of the sulfonylurea class. Glimepiride is a white to yellowish-white, crystalline, odorless to practically odorless ... A multiple-dose titration study was also conducted in 16 Type 2 diabetic patients with renal

NDC 16729-002 Glimepiride Glimepiride

AMARYL (glimepiride tablets) 1, 2, and 4 mg

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AMARYL® Rx Only (glimepiride tablets) 1, 2, and 4 mg ... A multiple-dose titration study was also conducted in 16 Type 2 diabetic patients with renal impairment using doses ranging from 1-8 mg daily for 3 months. The results were consistent with those observed after single doses. All patients with a CLcr less than 22 mL/min had

AMARYL (glimepiride tablets) 1, 2, and 4 mg

AMARYL Rx Only (glimepiride tablets) 1, 2, and 4 mg

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Baseline creatinine clearance ranged from 10 to 60 mL/min. The pharmacokinetics of glimepiride were evaluated in the multiple-dose titration study and the results were consistent with those observed in patients enrolled in a single-dose study. In both studies, the relative total clearance of glimepiride increased when kidney function was impaired.

AMARYL Rx Only (glimepiride tablets) 1, 2, and 4 mg

Glimepiride Oral : Uses, Side Effects, Interactions ...

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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. ... To demonstrate the superiority of sotagliflozin dose 1 compared to glimepiride on change in body weight, SBP (systolic blood pressure) in patients with baseline SBP ≥130 mmHg, SBP in all patients, and proportion of patients with ...

Glimepiride Oral : Uses, Side Effects, Interactions ...

NDC 42571-105 Glimepiride Glimepiride

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Efficacy of glimepiride/metformin fixed-dose combination vs metformin uptitration in type 2 diabetic patients inadequately controlled on low-dose metformin monotherapy: A randomized, open label ...

NDC 42571-105 Glimepiride Glimepiride

Efficacy and Safety of Sotagliflozin Versus Glimepiride ...

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Measuring Effectiveness of Glimepiride Titration Using SMBG in Patients The Open Diabetes Journal, 2009, Volume 2 39 values of 6.5% but <8% over several months before enrollment. The exclusion criteria included symptomatic coronary artery disease, cerebrovascular disease, renal failure, severe liver dysfunction, and heart failure.

Efficacy and Safety of Sotagliflozin Versus Glimepiride ...

(PDF) Efficacy of glimepiride/metformin fixed-dose ...

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Glimepiride is the generic name of the prescription drug Amaryl, used to treat patients with type 2 diabetes. Glimepiride belongs to a class of drugs known as sulfonylureas.. It stimulates the ...

(PDF) Efficacy of glimepiride/metformin fixed-dose ...

Open Access Measuring Effectiveness of Glimepiride ...

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Patients were randomized in a 2:1 ratio (using the lowest available treatment assignment number when eligibility was established) to receive 14 weeks of glimepiride or matching placebo once daily with continued diet/exercise. The starting glimepiride dose was 1 mg, with titration to 2 mg and 4 mg for FPG levels >120 mg/dL.

Open Access Measuring Effectiveness of Glimepiride ...

Glimepiride (Amaryl) - Side Effects, Dosage, Interactions ...

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Glimepiride is a CYP2C9 substrate; capecitabine and/or its metabolites are thought to be inhibitors of CYP2C9. In a drug interaction study, the mean AUC of another CYP2C9 substrate, S-warfarin (single dose), significantly increased after coadministration with capecitabine; the maximum observed INR value also increased by 91%.

Glimepiride (Amaryl) - Side Effects, Dosage, Interactions ...

Amaryl - FDA prescribing information, side effects and uses

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6/16/2010 · Initiation and Titration of Amaryl (AMIT KZ) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.

Amaryl - FDA prescribing information, side effects and uses

Efficacy and safety profile of glimepiride in Mexican ...

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10/1/2018 · A total daily dose of glimepiride≥1 mg will be divided and administered as two daily doses: one dose in the morning and one dose in the evening. If target fasting plasma glucose is not achieved during the drug-titration period, the dose of glimepiride will …

Efficacy and safety profile of glimepiride in Mexican ...

Glimepiride (glimepiride) dose, indications, adverse ...

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A key strength of this study is the up‐titration of glimepiride to reflect real‐world clinical practice. Although titration of sulphonylureas is essential to balance antihyperglycaemic efficacy with the risk of hypoglycaemia, it is not typical for clinical trials to allow continuous titration throughout the study.

Glimepiride (glimepiride) dose, indications, adverse ...

Initiation and Titration of Amaryl - Full Text View ...

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1/25/2019 · Baseline creatinine clearance ranged from 10 to 60 mL/min. The pharmacokinetics of glimepiride were evaluated in the multiple-dose titration study and the results were consistent with those observed in patients enrolled in a single-dose study. In both studies, the relative total clearance of glimepiride increased when kidney function was impaired.

Initiation and Titration of Amaryl - Full Text View ...
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